Anaquant HCP analysis I Protein characterisation I Protein analysis
We provide accurate mass of the antibody and the heavy and light chains before and after deglycosylation.
We provide accurate mass of the antibody and the heavy and light chains before and after deglycosylation.
At ANAQUANT, we specialize in providing top-tier Intact Mass Characterization using Liquid Chromatography-Mass Spectrometry (LC-MS). Our state-of-the-art technology and expert team ensure precise and reliable analysis of your biopharmaceutical products, verifying their molecular weight, purity, structural integrity, and stability.
What is Intact Mass Characterization?
Intact Mass Characterization is a crucial analytical technique that measures the molecular weight of proteins and biomolecules in their native, unfragmented state. This process is essential for:
Molecular Weight Verification: Confirming the correct molecular weight of your product.
Modification Detection: Identifying post-translational modifications (PTMs) and structural variants.
Purity Assessment: Detecting contaminants and degradation products to ensure sample purity.
Batch Consistency Monitoring: Ensuring uniformity across different production batches.
Drug Stability: Evaluating the stability of drug products under various conditions to ensure their efficacy and safety over time.
Our Workflow
Sample Preparation: Optimized protocols to maintain sample integrity.
Data Acquisition: High-resolution mass spectrometric analysis.
Data Analysis: Advanced software tools for accurate data interpretation.
Reporting: Detailed reports with comprehensive findings, including molecular weight, PTM identification, purity assessments, and stability data.
> Characterizing monoclonal antibodies, recombinant proteins, and therapeutic proteins.
> Ensuring product integrity and consistency.
> Evaluating how drug products maintain their quality, efficacy, and safety over time.