Application note

Improved monitoring of human protein expression using humanized mouse models by mass spectrometry

Application note May 29th, 2024

Host Cell Proteins (HCPs) identification and quantification inside AAV therapeutic drugs with HCPprofiler.

Application note April 3rd, 2024

41 Amino acids analysis in serum by LC-MS/MS

Application note March 29th, 2024

Comparison between a targeted LCMS and the label free HCPprofiler solution for quantification of HCPs

Application note March 19th, 2024

pharmacokinetic study of monoclonal antibodies in rat plasma: implementation of immunoprecipitation

Application note February 16th, 2024

Intact Mass Analysis of a monoclonal Antibody

Application note February 9th, 2024

HCPprofiler Standard: Repeatability Across All Considered Matrices

Application note October 23rd, 2023

A targeted method for specific quantification of 74 critical Host Cell Protein

Application note April 19th, 2023

Downstream process comparison between production sites

Application note November 10th, 2022

Bioproduction’s transfer and uspscale evaluation on HCPs content

Application note May 16th, 2022

Comparison of HCP quantification performances using either HCP-PROFILER based calibration curves or protein standard based calibration curves

Application note September 2nd, 2020

Impact of the upstream process on total amount and individual amount of HCP in the final drug products

Application note June 25th, 2020

Inter-laboratories reproducibility of protein quantification with HCP PROFILER

Application note June 11th, 2020

HCP profiler to evaluate impact of process scale up on Host Cell Protein quantity and identity

Application note June 5th, 2020

When targeted MS approach allows to detect unsuspected chemical modification during bioproduction

Application note May 11th, 2020

mAb aggregate and degradation income control using Size Exclusion Chromatography (SEC)

Application note April 7th, 2020

Quantification of 74 critical Host Cell Proteins with LC-MS and Scout MRM

Application note April 2nd, 2020

Reproducibility of Host Cell Protein quantification with HCP PROFILER solution

Application note March 11th, 2020

Host Cell Protein identification and quantification in drug substance batches consequently to Down Stream Process optimisation

Application note January 24th, 2020

Bioprocess characterization based on MS-based Multi Attribute Monitoring and HCP analysis

Application note January 16th, 2020

Fast and specific method to validate cell models: application to KO models

Application note December 16th, 2019

Why mass spectrometry is also a quantitative method?

Application note July 23rd, 2019

Accurate and specific quantification of targeted Host Cell Proteins

Application note June 19th, 2019

Residual protein taxonomy identification in cell & gene therapies

Application note June 10th, 2019

A multiplex identification and quantification of monoclonal antibodies

Application note June 10th, 2019

A specific identification and quantification of antigens in polyvalent vaccines

Application note June 10th, 2019

How to differentiate specific phosphorylation sites?

Application note June 10th, 2019

Early pk studies on recombinant proteins or peptides

Application note June 10th, 2019

Host Cell Proteins analysis for clinical batches comparison

Application note June 10th, 2019

Host Cell Proteins monitoring for biosimilar batch comparison

Application note June 10th, 2019

HCP monitoring for Down stream Process improvement

Application note June 10th, 2019

How LC-MS can bring specificity for biologics bioanalysis?

Application note May 9th, 2018

How to monitor your nano LC-MS system performance for proteomic analysis?

Application note May 2nd, 2018